CPB2 anticorps (AA 126-156)
Aperçu rapide pour CPB2 anticorps (AA 126-156) (ABIN452866)
Antigène
Voir toutes CPB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 126-156
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Specificité
- This antibody detects CPB2 (aa 126~156).
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Réactivité croisée (Details)
- Species reactivity (tested):Human,
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Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- KLH conjugated synthetic peptide selected between 126~156 amino acids from the Center region of Human CPB2
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Indications d'application
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ELISA: 1/1,000. Western blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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Autre désignation
- Carboxypeptidase B2
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Sujet
- Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.Synonyms: CPB2, CPU, Carboxypeptidase U, Plasma carboxypeptidase B, TAFI, Thrombin-activable fibrinolysis inhibitor, pCPB
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Poids moléculaire
- 48412 Da
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ID gène
- 1361
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NCBI Accession
- NP_001863
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UniProt
- Q96IY4
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Pathways
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
Antigène
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